Mucous membrane plasmacytosis

Mucous membrane plasmacytosis is a rare, idiopathic condition consisting of a dense plasma-cell infiltrate of the mucous membranes. Zoon first described a plasma-cell infiltrate occurring on the glans penis and plasmacytosis involving other body orifices have been reported under a variety of different terms. White et al. simplified the terminology by suggesting all plasma-cell infiltrates of the mucous membranes of body orifices be termed plasma-cell orificial mucositis. The differential diagnoses and treatment for mucous membrane plasmacytosis are summarized. A middle-aged female with an unusual plasma-cell proliferation disorder of the upper aerodigestive tract is reported for its rarity.